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SUMMARY:Computational Approaches in Functional Genomics: Understanding Gene Regulation and Development
DESCRIPTION:Statistical Bioinformatics SeminarDr Luca Pinello\, Harvard Medical School\n\n\n\n\n\n\n\n\n\n\n\nIn this talk\, Dr Luca Pinello will present an overview of his lab’s recent work at the intersection of CRISPR genome editing\, single-cell omics assays\, and generative AI to elucidate gene regulation. His lab’s research focuses on developing computational methods to investigate genotype-phenotype relationships at high resolution\, infer dynamic gene regulatory networks\, and integrate multi-omics data. By leveraging state-of-the-art technologies and advanced computational approaches\, his lab aims to uncover the complexities of cellular heterogeneity\, identify key regulatory elements and transcription factors\, and understand the interplay between chromatin structure and function in normal development and disease. \n\n\n\n\n\nThis is an online event held via Zoom.\n\n\n\n\nSubscribe to our seminar mailing list\n\n\n\n\n→\n\n\n\n\n\n\n\nFind out more about the Statistical Bioinformatics seminar series\n\n\n\n\n\n→\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\n\n\n\n\n\n\n\n\n\n\n \n\n\n\n\n\nDr Luca Pinello\n\n\n\nLuca Pinello is a computational biologist and leader in developing computational methods for functional genomics\, genome editing and single cell technologies. He holds a Ph.D. in Mathematics and Computer Science from University of Palermo\, Italy. He is currently an Associate Pathologist at Massachusetts General Hospital (MGH) and an Associate Professor of Pathology at Harvard Medical School. He is also part of the MGH Center for Cancer Research and an Associate Member of the BROAD Institute of MIT and Harvard. He has developed several foundational computational tools in the field of genome editing for the design (CRISPRme\, CRISPRitz\, PrimeDesign)\, quantification (CRISPResso 1 and 2)\, and analyses of coding and non-coding tiling screens (CRISPRO\, CRISPR-SURF). He was awarded one of the first NIH R35 Genomic Innovator Awards\, a prestigious grant supporting highly innovative researchers working on important problems in genomics. 
URL:https://spds.sydney.edu.au/event/statistical-bioinformatics-seminar-series/
CATEGORIES:Videos
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