Systematic comparison of sequencing-based spatial transcriptomic methods with cadasSTre and SpatialBen

Charles Perkins Centre, University of Sydney Johns Hopkins Dr, Sydney, NSW, Australia

Statistical Bioinformatics Seminar: Judith and David Coffey Speaker Speaker: Prof Matthew Ritchie (WEHI) Abstract: Sequencing-based Spatial Transcriptomics (sST) allows gene expression to be measured within complex tissue contexts. Although a wide array of sST technologies are currently available to researchers, efforts to comprehensively benchmark different platforms are currently lacking. The inherent variability across technologies and datasets poses challenges […]

High dimensional tensor methods for multi-modal single cell genomics data

Statistical Bioinformatics Seminar Speaker: Kwangmoon Park (University of Wisconsin-Madison) Abstract: Emerging single cell technologies that simultaneously capture long-range interactions of genomic loci together with their DNA methylation levels are advancing our understanding of 3D genome structure and its interplay with the epigenome at the single cell level. While methods to analyze data from single cell high […]